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In light buy anastrozole no prescription Melbourne of evidence showing the superiority of aromatase inhibitors over tamoxifen in postmenopausal women with early breast cancer, oncologists buy anastrozole no prescription Melbourne have revisited the role of ovarian suppression to optimize outcomes of premenopausal women, either in buy anastrozole no prescription Melbourne combination with tamoxifen or to facilitate treatment with an aromatase inhibitor.

Breast cancer buy anastrozole no prescription Melbourne remains the most common cancer among women. In the last two decades, the treatment of breast cancers has become buy anastrozole no prescription Melbourne personalized. This has been possible due to the subtyping of breast cancers. Breast cancers have been subtyped based on the receptors on the breast cancer cell. The most clinically significant receptors — those that have targeted therapies — are the estrogen and progesterone receptors and the human epidermal growth factor receptor. Cancers that have buy anastrozole no prescription Melbourne the estrogen and progesterone receptors are termed hormone receptor positive cancers.

The multiple buy anastrozole no prescription Melbourne prospective clinical trials involving AIs serve as a database upon which to consider their efficacy and toxicity. Postmenopausal buy anastrozole no prescription Melbourne patients with early breast cancer have two options for adjuvant endocrine therapy, tamoxifen and AIs. In considering the balance of efficacy and toxicities, the two outcomes will be considered individually. In terms of efficacy one can consider the endpoints of recurrence free buy anastrozole no prescription Melbourne survival, disease-free survival, breast cancer free survival, survival without recurrence, and overall survival.

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